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(R*,R*)- 3-Hydroxy-2-methylpentanoic Acid 1-Ethylpropyl Ester

Catalog Number ACM114715569
CAS 114715-56-9
Synonyms (2S,3R)-1-Ethyl Propyl 2-Methyl-3-hydroxypentanoate;(R*,R*)-3-Hydroxy-2-methylpentanoic Acid 1-Ethylpropyl Ester (9CI)
Molecular Weight 202.29
Molecular Formula C₁₁H₂₂O₃
Application (R*,R*)- 3-Hydroxy-2-methylpentanoic Acid 1-Ethylpropyl Ester is used in the synthesis of (±)-sitophilate via addition of propanal to the lithium enediolate of propanoic acid and subsequent esterification with 3-pentanol under standard Fischer conditions. (±)-sitophilate is an analog of the granary weevil aggregation pheromone.
References Cheskis, B.A.; et al.: Russ. Chem. Bull, 4, 807 (1990); Gil, S.; et al.: Synthesis, 19, 3451 (2005)
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